The effect of acute and 14-day exogenous ketone supplementation on glycemic control in adults with type 2 diabetes: two randomized controlled trials Journal Articles uri icon

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  • Exogenous ketone supplements can acutely lower blood glucose, suggesting therapeutic potential in individuals with impaired glucose metabolism. However, the effect of exogenous ketones on glucose metabolism in adults with type 2 diabetes has not been investigated in a controlled setting. In adults with type 2 diabetes, ketone monoester ingestion did not lower blood glucose acutely in a fasted state and did not improve glycemic control across thrice daily premeal ingestion across 14 days.


  • Falkenhain, Kaja
  • Oliveira, Barbara F
  • Islam, Hashim
  • Neudorf, Helena
  • Cen, Haoning H
  • Johnson, James D
  • Madden, Kenneth
  • Singer, Joel
  • Walsh, Jeremy
  • Little, Jonathan P

publication date

  • January 1, 2024