Microfluidic bioprinter for in-situ formation of engineered skin grafts for burn wound treatment

The standard of care for patients with full thickness burns is the application of acellular extracellular matrix materials which provide a temporary barrier against infection, but drawbacks include the high cost of treatment and the need for multiple surgeries. We report the development of a handheld bioprinter to organize fibrinogen and collagen based soft biomaterials through a microfluidic device to pattern mesenchymal stromal cells from …