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Abstract

Wound healing occurs as a response to disruption of the epidermis and dermis. It is an intricate and well-orchestrated response with the goal to restore skin integrity and function. However, in hundreds of millions of patients, skin wound healing results in abnormal scarring, including keloid lesions or hypertrophic scarring. Although the underlying mechanisms of hypertrophic scars and keloid lesions are not well defined, evidence suggests that …

Authors

Jeschke MG; Wood FM; Middelkoop E; Bayat A; Teot L; Ogawa R; Gauglitz GG

Journal

Nature Reviews Disease Primers, Vol. 9, No. 1,

Publisher

Springer Nature

DOI

10.1038/s41572-023-00474-x

ISSN

2056-676X