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Maternal First-Trimester Alpha-Fetoprotein and...
Journal article

Maternal First-Trimester Alpha-Fetoprotein and Placenta-Mediated Pregnancy Complications

Abstract

BACKGROUND: Maternal serum markers used for trisomy 21 screening are associated with placenta-mediated complications. Recently, there has been a transition from the traditional first-trimester screening (FTS) that included PAPP-A (pregnancy-associated plasma protein-A) and beta-hCG (human chorionic gonadotropin), to the enhanced FTS test, which added first-trimester AFP (alpha-fetoprotein) and PlGF (placental growth factor). However, whether …

Authors

Melamed N; Okun N; Huang T; Mei-Dan E; Aviram A; Allen M; Abdulaziz KE; McDonald SD; Murray-Davis B; Ray JG

Journal

Hypertension, Vol. 80, No. 11, pp. 2415–2424

Publisher

Wolters Kluwer

Publication Date

November 2023

DOI

10.1161/hypertensionaha.123.21568

ISSN

0194-911X