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Journal article

Liquid Transmission Electron Microscopy for Probing Collagen Biomineralization

Abstract

Collagen biomineralization is fundamental to hard tissue assembly. While studied extensively, collagen mineralization processes are not fully understood, with the majority of theories derived from electron microscopy (EM) under static, dehydrated, or frozen conditions, unlike the liquid phase environment where mineralization occurs. Herein, novel liquid transmission EM (TEM) strategies are presented, in which collagen mineralization was …

Authors

DiCecco L-A; Gao R; Gray JL; Kelly DF; Sone ED; Grandfield K

Journal

Nano Letters, Vol. 23, No. 21, pp. 9760–9768

Publisher

American Chemical Society (ACS)

Publication Date

November 8, 2023

DOI

10.1021/acs.nanolett.3c02344

ISSN

1530-6984