Journal article
Predictors of histologic response to mepolizumab in pediatric eosinophilic esophagitis
Abstract
BACKGROUND: Eosinophilic esophagitis (EoE) is a chronic, allergic disease of the esophagus. Current treatment options are limited. One experimental therapy is antibodies against interleukin-5 (IL-5). However, it is unknown why some patients respond to anti-IL-5 treatment whereas others do not. We sought to delineate predictors of histologic response to anti-IL-5 therapy in pediatric EoE.
METHODS: This post hoc analysis of a multicenter, …
Authors
Wong ECL; Gleave AL; Marshall JK; Narula N
Journal
European Journal of Gastroenterology & Hepatology, Vol. 35, No. 10, pp. 1131–1136
Publisher
Wolters Kluwer
Publication Date
October 2023
DOI
10.1097/meg.0000000000002623
ISSN
0954-691X