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Diagnostic Performance and Safety of...
Journal article

Diagnostic Performance and Safety of 18F-rhPSMA-7.3 Positron Emission Tomography in Men With Suspected Prostate Cancer Recurrence: Results From a Phase 3, Prospective, Multicenter Study (SPOTLIGHT)

Abstract

PURPOSE: SPOTLIGHT (NCT04186845) evaluated diagnostic performance and safety of radiohybrid 18F-rhPSMA-7.3, a novel high-affinity positron emission tomography radiopharmaceutical. MATERIALS AND METHODS: Men with prostate cancer recurrence underwent positron emission tomography/CT 50-70 minutes after intravenous administration of 296±20% MBq 18F-rhPSMA-7.3. To assess the coprimary end points (verified detection rate and combined region-level …

Authors

Jani AB; Ravizzini GC; Gartrell BA; Siegel BA; Twardowski P; Saltzstein D; Fleming MT; Chau A; Davis P; Chapin BF

Journal

Journal of Urology, Vol. 210, No. 2, pp. 299–311

Publisher

Wolters Kluwer

Publication Date

August 2023

DOI

10.1097/ju.0000000000003493

ISSN

0021-0005