Journal article
Effects of Treadmill Exercise on Cell Proliferation and Differentiation in the Subgranular Zone of the Dentate Gyrus in a Rat Model of Type II Diabetes
Abstract
In the present study, we investigated the effects of a treadmill exercise on serum glucose levels and Ki67 and doublecortin (DCX) immunoreactivity, which is a marker of cell proliferation expressed during cell cycles except G0 and early G1 and a marker of progenitors differentiating into neurons, respectively, in the subgranular zone of the dentate gyrus (SZDG) using a type II diabetic model. At 6 weeks of age, Zucker lean control (ZLC) and …
Authors
Yi SS; Hwang IK; Yoo K-Y; Park OK; Yu J; Yan B; Kim IY; Kim YN; Pai T; Song W
Journal
Neurochemical Research, Vol. 34, No. 6, pp. 1039–1046
Publisher
Springer Nature
Publication Date
6 2009
DOI
10.1007/s11064-008-9870-y
ISSN
0364-3190
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AnimalsBiomarkersBlood GlucoseBody WeightCell DifferentiationCell DivisionCell ProliferationDentate GyrusDiabetes Mellitus, Type 2Doublecortin Domain ProteinsDoublecortin ProteinEatingExercise TestFemaleInterphaseKi-67 AntigenLeptinMaleMicrotubule-Associated ProteinsNeurogenesisNeuronsNeuropeptidesPhysical Conditioning, AnimalRatsRats, ZuckerStem Cells