Journal article
Lipidomic analysis of skeletal muscle tissues of p53 knockout mice by nUPLC-ESI-MS/MS
Abstract
Tumour suppressor p53 is known to be associated with the maintenance of mitochondrial functional properties in the skeletal muscles. As deactivation or mutation of p53 can affect the synthesis of lipids, investigating the relationship between p53-related energy generation metabolism and perturbation of lipid profile is critical. In this study, 329 lipid species (among 412 identified species) in two different skeletal muscle tissues (the …
Authors
Park SM; Byeon SK; Lee H; Sung H; Kim IY; Seong JK; Moon MH
Journal
Scientific Reports, Vol. 7, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41598-017-02065-9
ISSN
2045-2322