Journal article
RUNX1 mutation in a patient with myelodysplastic syndrome and decreased erythrocyte expression of blood group A antigen
Abstract
BACKGROUND: Loss of blood group ABO antigens on red blood cells (RBCs) is well known in patients with leukemias, and such decreased ABO expression has been reported to be strongly associated with hypermethylation of the ABO promoter. We investigated the underlying mechanism responsible for A-antigen reduction on RBCs in a patient with myelodysplastic syndrome.
STUDY DESIGN AND METHODS: Genetic analysis of ABO was performed by PCR and sequencing …
Authors
Hayakawa A; Sano R; Takahashi Y; Kubo R; Harada M; Omata M; Yokohama A; Handa H; Tsukada J; Takeshita H
Journal
Transfusion, Vol. 60, No. 1, pp. 184–196
Publisher
Wiley
Publication Date
1 2020
DOI
10.1111/trf.15628
ISSN
0041-1132