Conference
Decreased production of neutrophil defensins and increased bacterial translocation in severely burned patients (89.33)
Abstract
Abstract α-Defensins are antimicrobial peptides produced by human neutrophils (HNPs). Because severely burned patients are greatly susceptible to gut-associated infections, in this study, the role of HNPs on the resistance of burn patients to bacterial translocation was investigated. PMN were isolated from peripheral blood of severely burned patients, as previously described. These cells (2 x 106 cells/mouse) were inoculated to X-irradiated and …
Authors
Kobayashi M; Yoshida S; Jeschke M; Inatsu A; Herndon D; Suzuki F
Volume
184
Pagination
pp. 89.33-89.33
Publisher
Oxford University Press (OUP)
Publication Date
April 1, 2010
DOI
10.4049/jimmunol.184.supp.89.33
Conference proceedings
The Journal of Immunology
Issue
1_Supplement
ISSN
0022-1767