The discovery and characterization of a novel scaffold as a potent hepatitis C virus inhibitor Journal Articles uri icon

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abstract

  • A novel anti-HCV benzothiazole scaffold was discovered by phenotypic screening. Further target characterization and structural optimization led to the identification of potent anti-HCV molecules targeting NS5A.

authors

  • Liu, Na
  • Zhu, Shiping
  • Zhang, Xianghua
  • Yin, Xunkui
  • Dong, Guoqiang
  • Yao, Jianzhong
  • Miao, Zhenyuan
  • Zhang, Wannian
  • Zhang, Xiaonan
  • Sheng, Chunquan

publication date

  • February 25, 2016