Andrographolide Inhibition of Th17‐Regulated Cytokines and JAK1/STAT3 Signaling in OVA‐Stimulated Asthma in Mice

Asthma has long been considered a disease of airway inflammation. The excessive or prolonged production of inflammatory mediators can result in airway remodeling and severe clinical syndromes such as dyspnea or even apnea. Therefore, pharmaceutical intervention is required to restrain the excessive release of such inflammatory mediators in control of asthma. Novel therapeutics and mechanistic insight are sought for the management of this …