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Peptidoglycan synthesis and structure in...
Journal article

Peptidoglycan synthesis and structure in Staphylococcus haemolyticus expressing increasing levels of resistance to glycopeptide antibiotics

Abstract

The structures of cytoplasmic peptidoglycan precursor and mature peptidoglycan of an isogenic series of Staphylococcus haemolyticus strains expressing increasing levels of resistance to the glycopeptide antibiotics teicoplanin and vancomycin (MICs, 8 to 32 and 4 to 16 microg/ml, respectively) were determined. High-performance liquid chromatography, mass spectrometry, amino acid analysis, digestion by R39 D,D-carboxypeptidase, and N-terminal …

Authors

Billot-Klein D; Gutmann L; Bryant D; Bell D; Van Heijenoort J; Grewal J; Shlaes DM

Journal

Journal of Bacteriology, Vol. 178, No. 15, pp. 4696–4703

Publisher

American Society for Microbiology

Publication Date

August 1996

DOI

10.1128/jb.178.15.4696-4703.1996

ISSN

0021-9193