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White matter hyperintensities and smaller cortical...
Journal article

White matter hyperintensities and smaller cortical thickness are associated with neuropsychiatric symptoms in neurodegenerative and cerebrovascular diseases

Abstract

BackgroundNeuropsychiatric symptoms (NPS) are a core feature of most neurodegenerative and cerebrovascular diseases. White matter hyperintensities and brain atrophy have been implicated in NPS. We aimed to investigate the relative contribution of white matter hyperintensities and cortical thickness to NPS in participants across neurodegenerative and cerebrovascular diseases.MethodsFive hundred thirteen participants with one of these conditions, …

Authors

Ozzoude M; Varriano B; Beaton D; Ramirez J; Adamo S; Holmes MF; Scott CJM; Gao F; Sunderland KM; McLaughlin P

Journal

Alzheimer's Research & Therapy, Vol. 15, No. 1,

Publisher

Springer Nature

DOI

10.1186/s13195-023-01257-y

ISSN

1758-9193