Evaluating response to interventions for vasomotor symptoms in patients with breast cancer: A patient-centered approach.

e24126 Background: Vasomotor symptoms (VMS), such as hot flashes, are a common reason for early discontinuation of endocrine therapy for patients (pts) with breast cancer (BC). The optimal intervention for VMS remains unknown. Using a novel symptom change analysis and regression trees, we examined whether clinically important change in VMS severity depends on baseline symptomatology. Methods: In this prospective study, pts …