Effect of a Package of Risk-Based Pharmaceutical and Lifestyle Interventions on Patients with Hypertension and/or Diabetes in Rural China: A Pragmatic Cluster Randomised Controlled Trial

Background: Primary prevention of cardiovascular disease (CVD) requires adequate control of hypertension and diabetes. We designed and implemented pharmaceutical and healthy lifestyle interventions for patients with diabetes and/or hypertension in rural primary care, and assessed their effectiveness at reducing the rate of severe CVD events. Methods: We used a pragmatic, parallel group, two-arm, controlled, superiority, cluster trial design. We …