Enhancing Osseointegration and Mitigating Bacterial Biofilms on Medical-Grade Titanium with Chitosan-Conjugated Liquid-Infused Coatings

Titanium alloys, in particular, medical-grade Ti-6Al-4V is heavily used in orthopaedic applications due to its high moduli, strength, and biocompatibility. Implant infection can result in biofilm formation and failure of prosthetics. The formation of a biofilm on implants protect bacteria from antibiotics and the immune response, resulting in the propagation of the infection and ultimately result in device failure. Recently, slippery …