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Heat stress modulates and protects hepatocyte...
Journal article

Heat stress modulates and protects hepatocyte membrane proteins during sepsis

Abstract

Introduction. Hepatic failure is one of the important features of septic multiorgan dysfunction. Previous studies have shown that, in septic rats, heat stress (HS) has a protective effect on bile acid transporters in hepatocyte membranes. This study investigates the influence of HS on hepatocyte membrane proteins, including the transporters oatp and mrp2, during endotoxemia. Methods. Endotoxemia in rats was induced by intraperitoneal injection …

Authors

Przkora R; Jeschke M; Haslbeck M; Heyde C; Ertel W; Herndon D; Bolder U; Herndon D

Journal

Journal of Surgical Research, Vol. 121, No. 2, pp. 334–335

Publisher

Elsevier

Publication Date

October 2004

DOI

10.1016/j.jss.2004.07.218

ISSN

0022-4804