74 Adipose Tissue from Burn Patients is Proinflammatory, Lipolytic and a Key Initiator of Hepatic Dysfunction

Severe burns induce systemic dysfunction characterized by chronic increased resting energy expenditure, catabolism of fat and muscle tissues, hepatomegaly and liver damage. The role of adipose tissue in initiating these complications has not been adequately defined. The aims of this study were to characterize the adipose tissue secretome of burn patients and delineate the extent of damage these biomolecules exert on hepatocytes compared to …