Integrating Affymetrix microarray data sets using probe-level test statistic for predicting prostate cancer

Microarray technology has previously been used to identify differentially expressed genes between tumor and normal prostate samples in a single study as well as in a synthesis involving multiple studies. When integrating results from several Affymetrix microarray datasets, previous studies have used probeset-level data which may lead to a loss of information contained at the probe-level. Here, we propose a new approach for combining results …