Gene expression profiling of the RAS in myoblasts following differentiation and mechanical stretch

Recent evidence, using animal models, suggests that angiotensin II can positively influence skeletal muscle hypertrophy. We conducted a genetic profile of RAS family members during C2C12 myoblast proliferation and differentiation. We also examined RAS family member gene expression following 4h of mechanical stretch. Both angiotensin II receptors (AT1 and AT2) were expressed in proliferating and differentiating myobasts and were significantly …