The total synthesis of a technetium chelate - tamoxifen complex Academic Article uri icon

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abstract

  • A potential agent for imaging breast cancer has been synthesized by derivatization of the anti-estrogen tamoxifen. A multistep synthesis was required to conjugate a technetium chelate to tamoxifen in such a fashion that the biodistribution of the complex should mimic that of the parent compound.Key words: tamoxifen, radioimaging, technetium, synthesis.

publication date

  • January 1, 1999