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The medicinal chemistry of carboranes
Journal article

The medicinal chemistry of carboranes

Abstract

The medicinal chemistry of dicarba-closo-dodecaboranes (otherwise referred to as carboranes) has traditionally centered on their use in boron neutron capture therapy (BNCT). More recently, work has begun to exploit the unique chemical and physical properties of carboranes for the preparation of novel inorganic pharmaceuticals and biological probes. This review is designed to highlight some of the recent work concerning medicinal carborane …

Authors

Valliant JF; Guenther KJ; King AS; Morel P; Schaffer P; Sogbein OO; Stephenson KA

Journal

Coordination Chemistry Reviews, Vol. 232, No. 1-2, pp. 173–230

Publisher

Elsevier

Publication Date

10 2002

DOI

10.1016/s0010-8545(02)00087-5

ISSN

0010-8545