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Structure and Biosynthesis of Nerve Growth Factor
Journal article

Structure and Biosynthesis of Nerve Growth Factor

Abstract

The first description of nerve growth factor (NGF) by Levi-Montalcini and Hamburger (1953) was of a factor from mouse sarcoma cells (S-180 and S-37) that elicited extensive growth of chick embryo neurons. Shortly thereafter, a serendipitous use of snake venom in the purification of this factor led Cohen to the discovery that NGF was present in moccasin snake venom as well (Cohen and Levi-Montalcini 1956). The finding that the mouse submaxillary …

Authors

Fahnestock M

Journal

Current Topics in Microbiology and Immunology, Vol. 165, , pp. 1–26

Publisher

Springer Nature

Publication Date

1991

DOI

10.1007/978-3-642-75747-1_1

ISSN

0070-217X