Journal article
Effects of peroxide and superoxide on coronary artery: ANG II response and sarcoplasmic reticulum Ca2+ pump
Abstract
The sarcoplasmic reticulum (SR) Ca2+ pump in membranes isolated from arterial smooth muscle is damaged by reactive oxygen species (ROS). Because angiotensin II (ANG II) contracts arterial smooth muscle by mobilizing intracellular Ca2+ concentrations ([Ca2+])i, we determined the effects of ROS pretreatment on ANG II-induced contractions in coronary artery rings and [Ca2+]i transients in smooth muscle cells (SMC) cultured from them. This …
Authors
Grover AK; Samson SE; Fomin VP; Werstiuk ES
Journal
American Journal of Physiology, Vol. 269, No. 3, pp. c546–c553
Publisher
American Physiological Society
Publication Date
September 1, 1995
DOI
10.1152/ajpcell.1995.269.3.c546
ISSN
0002-9513