Journal article
Blood-Pressure Lowering in Intermediate-Risk Persons without Cardiovascular Disease
Abstract
BACKGROUND: Antihypertensive therapy reduces the risk of cardiovascular events among high-risk persons and among those with a systolic blood pressure of 160 mm Hg or higher, but its role in persons at intermediate risk and with lower blood pressure is unclear.
METHODS: In one comparison from a 2-by-2 factorial trial, we randomly assigned 12,705 participants at intermediate risk who did not have cardiovascular disease to receive either …
Authors
Lonn EM; Bosch J; López-Jaramillo P; Zhu J; Liu L; Pais P; Diaz R; Xavier D; Sliwa K; Dans A
Journal
New England Journal of Medicine, Vol. 374, No. 21, pp. 2009–2020
Publisher
Massachusetts Medical Society
Publication Date
May 26, 2016
DOI
10.1056/nejmoa1600175
ISSN
0028-4793