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A systematic review and meta-analysis of...
Journal article

A systematic review and meta-analysis of anti-pseudomonal penicillins and carbapenems in pediatric febrile neutropenia

Abstract

PurposeCarbapenems represent a broad-spectrum alternative to anti-pseudomonal penicillin (APP) combination or single-agent therapy for the management of pediatric febrile neutropenia (FN). Our primary objective was to describe the risk of treatment failure in children treated with an APP or carbapenem as initial empiric treatment for FN. Our secondary objective was to compare outcomes of APP versus carbapenem therapy in this …

Authors

Manji A; Lehrnbecher T; Dupuis LL; Beyene J; Sung L

Journal

Supportive Care in Cancer, Vol. 20, No. 10, pp. 2295–2304

Publisher

Springer Nature

Publication Date

10 2012

DOI

10.1007/s00520-011-1333-3

ISSN

0941-4355