The use of a neural network to determine tissue optical properties from spatially resolved diffuse reflectance measurements

The authors report a novel application of a neural network to perform curve fitting to simulated experimental data, obviating the need for lengthy non-linear least-squares fitting procedures. This application arose in the non-invasive determination of tissue optical properties, namely the transport scattering coefficient, mu 's and the absorption coefficient, mu a. This problem is relevant in clinical applications such as photodynamic therapy …