Journal article
Sex-Dependent Differences in Serum Autoantibody Levels in the 3×Tg-AD Model of Alzheimer’s Disease
Abstract
Abstract Sex-dependent discrepancies in disease prevalence and serum autoantibody levels are observed in patients and animal models of Alzheimer’s disease (AD). The present study examines whether gonadal hormones play a role in sex differences in serum autoantibody levels in the 3×Tg-AD mouse model of AD. 3×Tg-AD and wild-type (WT) mice were gonadectomised or sham-operated at 3 months of age. After behavioural phenotyping at 6 months of age, …
Authors
Ma D; Song W; Michalski B; Sakic B; Fahnestock M
Journal
The Journal of Immunology, Vol. 208, No. Supplement_1, pp. 108.14–108.14
Publisher
Oxford University Press (OUP)
Publication Date
May 1, 2022
DOI
10.4049/jimmunol.208.supp.108.14
ISSN
0022-1767