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Journal article

Behavioral effects of 5-hydroxy-N-acetyltryptophan, a putative synthetic precursor of N-acetylserotonin

Abstract

1. Adult male rats were injected with either 5-hydroxy-N-acetyltryptophan (5-OHNAT), a synthetic putative precursor of N-acetylserotonin, or 5-hydroxytryptophan (5-HTP), the serotonin precursor, and behavioral effects were observed. Pretreatment consisted of carbidopa and nialamide. 2. The behavioral effects of systemic injections of 5-OHNAT and 5-HTP were qualitatively similar i.e. head weaving, forepaw treading, etc., but the effect of …

Authors

Burns TG; Szechtman H; Brown GM; Snieckus V

Journal

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 6, No. 4-6, pp. 359–363

Publisher

Elsevier

Publication Date

January 1982

DOI

10.1016/s0278-5846(82)80107-3

ISSN

0278-5846