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Journal article

Effectiveness and Duration of Protection of a Fourth Dose of Coronavirus Disease 2019 Messenger RNA Vaccine Among Long-term Care Residents in Ontario, Canada

Abstract

We estimated the effectiveness of a fourth dose of messenger RNA coronavirus disease 2019 vaccine against Omicron infections and severe outcomes over time among long-term care residents in Ontario, Canada. Fourth doses provide additional protection against Omicron-related outcomes, but the protection wanes over time, with more waning seen against infection than severe outcomes.

Authors

Grewal R; Nguyen L; Buchan SA; Wilson SE; Costa AP; Kwong JC

Journal

The Journal of Infectious Diseases, Vol. 227, No. 8, pp. 977–980

Publisher

Oxford University Press (OUP)

Publication Date

April 18, 2023

DOI

10.1093/infdis/jiac468

ISSN

0022-1899