Journal article
Characterization of 7-ethoxycoumarin-O-deethylase from malathion resistant and susceptible strains of Drosophila melanogaster
Abstract
Mixed-function oxidase activity in a D. melanogaster strain carrying at least two closely linked malathion resistance genes on chromosome 3 was compared with the susceptible Canton S strain. The kinetics of O-deethylation of 7-ethoxycoumarin (7-ECD activity) with respect to pH, temperature, substrate and cofactor (NADPH) affinities and the response to metal salts of both strains were similar. The resistant strain had approx. 5-fold greater …
Authors
Patil TN; Morton RA; Singh RS
Journal
Insect Biochemistry and Molecular Biology, Vol. 20, No. 1, pp. 91–98
Publisher
Elsevier
Publication Date
January 1990
DOI
10.1016/0020-1790(90)90024-o
ISSN
0965-1748