865P The Significance of Complete Response (Cr) in Patients Receiving Salvage Therapy for Advanced Urothelial Carcinoma (Uc)

Aim: Molecular interrogation of tumors showing CR with salvage therapy for UC may provide insights regarding biology, as suggested by the discovery of TSC1 mutations in those with durable CR on everolimus. We hypothesized that CR with salvage therapy is robustly associated with long term outcomes, and may represent an intermediate endpoint and identify tumors warranting molecular interrogation. Methods: Phase II trials of salvage chemotherapy …