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Radiation-Induced Apoptosis in Human Lymphocytes
Journal article

Radiation-Induced Apoptosis in Human Lymphocytes

Abstract

We have tested the possibility of using apoptosis (programmed cell death) in human peripheral blood lymphocytes as a short-term biological dosimeter. Lymphocytes isolated from whole blood were irradiated in culture with 250 kVp x-rays or 60Co gamma rays. Two assays were used to measure apoptosis in lymphocytes after irradiation: in situ terminal deoxynucleotidyl transferase assay and fluorescence analysis of DNA unwinding assay. Similar …

Authors

Boreham DR; Gale KL; Maves SR; Walker JA; Morrison DP

Journal

Health Physics, Vol. 71, No. 5, pp. 685–691

Publisher

Wolters Kluwer

Publication Date

November 1996

DOI

10.1097/00004032-199611000-00007

ISSN

0017-9078