Journal article
Anticoagulation for pregnant women with mechanical heart valves: a systematic review and meta-analysis
Abstract
AIMS: To review maternal and foetal outcomes in women with mechanical heart valves (MHVs) treated with vitamin-K antagonists (VKAs), first-trimester heparin followed by VKAs (sequential treatment), low molecular weight heparin (LMWH) and unfractionated heparin (UFH) during pregnancy, in order to inform practice.
METHODS AND RESULTS: Medline, Embase and Central were searched from inception until February 2016. Two reviewers independently …
Authors
D’Souza R; Ostro J; Shah PS; Silversides CK; Malinowski A; Murphy KE; Sermer M; Shehata N
Journal
European Heart Journal, Vol. 38, No. 19, pp. 1509–1516
Publisher
Oxford University Press (OUP)
Publication Date
May 14, 2017
DOI
10.1093/eurheartj/ehx032
ISSN
0195-668X