Human Gut Metagenomes Encode Diverse GH156 Sialidases Journal Articles

abstract

• Sialic acids occupy terminal positions of human glycans where they act as receptors for microbes, toxins, and immune signaling molecules. Microbial enzymes that remove sialic acids, sialidases, are abundant in the human microbiome where they may contribute to shaping the microbiota community structure or contribute to pathology.

authors

• Mann, Evan
• Shekarriz, Shahrokh
• Surette, Michael

status

• published 

publication date

• December 13, 2022

has subject area

• Gastrointestinal Microbiome (MeSH)
• Glycoside Hydrolases (MeSH)
• Humans (MeSH)
• Metagenome (MeSH)
• Microbiology (Science Metrix)
• Neuraminidase (MeSH)
• Polysaccharides (MeSH)
• Sialic Acids (MeSH)

published in

• Applied and Environmental Microbiology  Journal

keywords

• GH156
• Gastrointestinal Microbiome
• Glycoside Hydrolases
• Humans
• Metagenome
• Neuraminidase
• Polysaccharides
• Sialic Acids
• glycoside hydrolase
• human microbiome
• inflammatory bowel disease
• microbiome
• sialic acid
• sialidase

Digital Object Identifier (DOI)

• 10.1128/aem.01755-22

start page

• e0175522

volume

• 88

issue

• 23