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Risk factors associated with prevalent vertebral...
Journal article

Risk factors associated with prevalent vertebral fractures in Duchenne muscular dystrophy

Abstract

Patients with Duchenne muscular dystrophy (DMD) have a high fracture burden due to progressive myopathy and steroid-induced osteoporosis. This study in males with DMD showed that markers of systemic glucocorticoid exposure including shorter stature, greater bone age delay, and lower lumbar spine bone mineral density were associated with spine fragility.Introduction Fragility  fractures are frequent in DMD. The purpose of this study was to …

Authors

Phung K; McAdam L; Ma J; McMillan HJ; Jackowski S; Scharke M; Matzinger M-A; Shenouda N; Koujok K; Jaremko JL

Journal

Osteoporosis International, Vol. 34, No. 1, pp. 147–160

Publisher

Springer Nature

Publication Date

January 2023

DOI

10.1007/s00198-022-06578-6

ISSN

0937-941X