Journal article
Quantitative Muscle Analysis in FSHD Using Whole-Body Fat-Referenced MRI
Abstract
BACKGROUND AND OBJECTIVES: Facioscapulohumeral muscular dystrophy (FSHD) is a rare, debilitating disease characterized by progressive muscle weakness. MRI is a sensitive assessment of disease severity and progression. We developed a quantitative whole-body (WB) musculoskeletal MRI (WB-MSK-MRI) protocol analyzing muscles in their entirety. This study aimed to assess WB-MSK-MRI as a potential imaging biomarker providing reliable measurements of …
Authors
Mellion ML; Widholm P; Karlsson M; Ahlgren A; Tawil R; Wagner KR; Statland JM; Wang L; Shieh PB; van Engelen BGM
Journal
Neurology, Vol. 99, No. 9, pp. e877–e889
Publisher
Wolters Kluwer
Publication Date
August 30, 2022
DOI
10.1212/wnl.0000000000200757
ISSN
0028-3878