Differential actions of diuretic factors on the Malpighian tubules of Rhodnius prolixus

The effects of corticotropin-releasing factor (CRF)-related (ZooneDH), calcitonin (CT)-related (RhoprDH(31)) and kinin-related (leucokinin I) peptides on the ion composition of fluid secreted by upper Rhodnius prolixus Malpighian tubules and on KCl reabsorption by the lower tubules were assessed. ZooneDH stimulated fluid secretion while increasing the [Na(+)] of secreted fluid at the expense of [K(+)]. Upper tubules responded to ZooneDH with a …