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BNT162b2 against COVID-19 in Brazil using a...
Journal article

BNT162b2 against COVID-19 in Brazil using a test-negative design: Study protocol and statistical analysis plan

Abstract

INTRODUCTION: Real-world data on COVID-19 vaccine effectiveness are needed to validate evidence from randomized clinical trials. Accordingly, this study aims to evaluate, in a real-world setting in Brazil, the effectiveness of Pfizer-BioNTech BNT162b2 against symptomatic COVID-19 and COVID-19-related complications across diverse populations. MATERIALS AND METHODS: A test-negative case-control study with follow-up of cases is currently being …

Authors

Rosa RG; Spinardi J; Allen KE; Manfio J; de Araujo CLP; Cohen M; Robinson CC; Sganzerla D; Ferreira D; de Souza EM

Journal

PLOS ONE, Vol. 17, No. 10,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0276384

ISSN

1932-6203