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Anomalous sedimentation of high molecular weight...
Journal article

Anomalous sedimentation of high molecular weight denatured mammalian DNA

Abstract

High molecular weight mammalian DNA (of greater than 5 × 108 daltons) appears to sediment anomalously in alkaline sucrose density gradients if centrifugation is at high speed. More accurate sedimentation profiles of this DNA may be obtained following low speed centrifugation.

Authors

McBurney MW; Graham FL; Whitmore GF

Journal

Biochemical and Biophysical Research Communications, Vol. 44, No. 1, pp. 171–177

Publisher

Elsevier

Publication Date

7 1971

DOI

10.1016/s0006-291x(71)80174-2

ISSN

0006-291X