Journal article
The Kinetics of Synthesis of Early Viral Proteins in KB Cells Infected with Wild-type and Transformation-defective Host-range Mutants of Human Adenovirus Type 5
Abstract
We have studied the kinetics of early adenovirus type 5 (Ad5) protein synthesis during lytic infection of KB cells by wild-type (wt) and transformation-defective host-range (hr) mutants. Proteins encoded within four early regions were studied: early region 1A (E1A: 1.5 to 4.5 map units, mu), E1B (4.5 to 11.2 mu), E2A (61.6 to 74.9 mu), and E4 (91.4 to 99.1 mu). Synthesis of E1A products, the first to appear during wt lytic infection, was …
Authors
Rowe DT; Branton PE; Graham FL
Journal
Journal of General Virology, Vol. 65, No. 3, pp. 585–597
Publisher
Microbiology Society
Publication Date
March 1, 1984
DOI
10.1099/0022-1317-65-3-585
ISSN
0022-1317