Journal article
Prion Diseases and the Gastrointestinal Tract
Abstract
The gastrointestinal (GI) tract plays a central role in the pathogenesis of transmissible spongiform encephalopathies. These are human and animal diseases that include bovine spongiform encephalopathy, scrapie and Creutzfeldt-Jakob disease. They are uniformly fatal neurological diseases, which are characterized by ataxia and vacuolation in the central nervous system. Although they are known to be caused by the conversion of normal cellular …
Authors
Davies GA; Bryant AR; Reynolds JD; Jirik FR; Sharkey KA
Journal
Canadian Journal of Gastroenterology and Hepatology, Vol. 20, No. 1, pp. 18–24
Publisher
Hindawi
Publication Date
2006
DOI
10.1155/2006/184528
ISSN
2291-2789