Journal article
Placebo Rates in Randomized Controlled Trials of Proctitis Therapy: A Systematic Review and Meta-Analysis Placebo Response in Proctitis
Abstract
BACKGROUND AND AIMS: Treatment options for proctitis are limited. To assist trial design for novel therapeutics, we conducted a systematic review and meta-analysis of proctitis randomized controlled trials [RCTs] to quantify placebo rates and identify factors influencing them.
METHODS: We searched MEDLINE, EMBASE and CENTRAL from inception to June 2021. Placebo-controlled trials of pharmacological interventions for proctitis were eligible. …
Authors
De Silva TA; Alphonsus L; Ma C; Hogan M; Sedano R; Narula N; Danese S; Peyrin-Biroulet L; MacDonald JK; Singh S
Journal
Journal of Crohn's and Colitis, Vol. 17, No. 1, pp. 123–136
Publisher
Oxford University Press (OUP)
Publication Date
January 27, 2023
DOI
10.1093/ecco-jcc/jjac109
ISSN
1197-4982