Journal article
SYST-15 TARGETING AXONAL GUIDANCE WITH ANTI-ROBO1 CAR T CELLS: A NEW THERAPEUTIC STRATEGY FOR MALIGNANT BRAIN CANCER
Abstract
Abstract
No standardized treatments exist for patients with treatment-refractory brain metastasis, glioblastoma and other recurrent brain tumours. Given the aggressive nature of these diseases and difficulty in modelling tumour recurrence, minimal efforts have been made to design rational therapies against them. Neurodevelopmental pathways are often highjacked and go awry in the progression of these cancers. The roundabout …
Authors
Brakel B; Chokshi C; Rossotti M; Venugopal C; Salim S; Mobilio D; Chafe S; Henry K; Singh S
Journal
Neuro-Oncology Advances, Vol. 4, No. Supplement_1, pp. i24–i24
Publisher
Oxford University Press (OUP)
Publication Date
August 5, 2022
DOI
10.1093/noajnl/vdac078.094
ISSN
0801-3284