Journal article
Cell Growth Inhibition upon Deletion of Four Toxin-Antitoxin Loci from the Megaplasmids of Sinorhizobium meliloti
Abstract
Toxin and antitoxin (TA) gene pairs are addiction systems that are present in many microbial genomes. Sinorhizobium meliloti is an N2-fixing bacterial symbiont of alfalfa and other leguminous plants, and its genome consists of three large replicons, a circular chromosome (3.7 Mb) and the megaplasmids pSymA (1.4 Mb) and pSymB (1.7 Mb). S. meliloti carries 211 predicted type II TA genes, each encoding a toxin or an antitoxin. We constructed …
Authors
Milunovic B; diCenzo GC; Morton RA; Finan TM
Journal
Journal of Bacteriology, Vol. 196, No. 4, pp. 811–824
Publisher
American Society for Microbiology
Publication Date
February 15, 2014
DOI
10.1128/jb.01104-13
ISSN
0021-9193