Neural Growth, Neural Damage and Neurotrophins in the Kindling Model of Epilepsy

Kindling is most frequently cited as a model of complex partial seizures with secondary generalization. As pointed out by Racine and Burnham,119 however, there are a wide variety of clinical events that are suitably modeled by kindling phenomena. We will begin with a brief description of some of these phenomena. Readers familiar with kindling may wish to jump ahead to the section on mechanisms—recent work.