Journal article
Unique changes in synaptic morphology following tetanization under pharmacological blockade
Abstract
Long-term potentiation (LTP) in the hippocampus has been associated with changes in synaptic morphology. Whether these changes are LTP-dependent or simply a result of electrophysiological stimulation has not yet been fully determined. This study involved an examination of synaptic morphology in the rat dentate gyrus 24 h after electrophysiological stimulation sufficient to induce LTP. In one group, ketamine, a competitive NMDA antagonist, was …
Authors
Weeks ACW; Ivanco TL; Leboutillier JC; Marrone DF; Racine RJ; Petit TL
Journal
Synapse, Vol. 47, No. 1, pp. 77–86
Publisher
Wiley
Publication Date
January 2003
DOI
10.1002/syn.10113
ISSN
0887-4476