Journal article
Anti-GD2 antibody for radiopharmaceutical imaging of osteosarcoma
Abstract
PurposeOsteosarcoma (OS) is the most frequently diagnosed bone cancer in children with little improvement in overall survival in the past decades. The high surface expression of disialoganglioside GD2 on OS tumors and restricted expression in normal tissues makes it an ideal target for anti-OS radiopharmaceuticals. Since human and canine OS share many biological and molecular features, spontaneously occurring OS in canines has been an ideal …
Authors
Fu Y; Yu J; Liatsou I; Du Y; Josefsson A; Nedrow JR; Rindt H; Bryan JN; Kraitchman DL; Sgouros G
Journal
European Journal of Nuclear Medicine and Molecular Imaging, Vol. 49, No. 13, pp. 4382–4393
Publisher
Springer Nature
Publication Date
November 2022
DOI
10.1007/s00259-022-05888-5
ISSN
1619-7070